Abstracts - Posters

Lille - Thursday Nov. 03, 2022 

p-001 Alexander Santillo Tau Positron Emission Tomography with [18F]RO948 in Frontotemporal Dementia
p-002 Tiffini Voss Adeno-associated viral vector serotype 1 (AAV1) gene therapy for FTD-GRN: a phase 1b dose-escalation study to assess safety, tolerability, and pharmacodynamic effects of PBFT02
p-003 Helene Pouclet-Courtemanche Idiopathic normal pressure hydrocephalus and behavioral variant of frontotemporal lobar degeneration: an unexpected association
p-004 Jackie Poos Longitudinal brain atrophy rates in presymptomatic genetic frontotemporal dementia using normative brain volumetry software
p-005 Sonja Soskic Extracting thalamic subregional volumes from structural and diffusion MRIs: application to the GENFI cohort
p-006 Barbara Borroni European Inter-Societal Delphi Consensus for the biomarker-based etiological diagnosis of neurocognitive disorders
p-007 Barbara Spencer Modules of genotypic variance reflect anatomic heterogeneity across the FTD-ALS spectrum
p-008 Xulin Liu Coupling between cerebral blood flow and grey matter volume relates to cognition in presymptomatic genetic frontotemporal dementia
p-009 Martina Bocchetta White matter microstructural changes in presymptomatic and symptomatic FTD using neurite orientation dispersion and density imaging
p-010 Júlia Faura Short- and long-read transcriptomics in FTLD-TDP identifies unique disease-associated transcripts generated by aberrant splicing
p-011 Alma Ghirelli Profiling morphologic MRI features of motor neuron disease caused by TARDBP mutations
p-012 Giordano Cecchetti EEG correlates in the three variants of primary progressive aphasia
p-013 ELISA CANU Social cognition in primary progressive aphasia
p-014 Federica Sorrentino MiRNA expression profile in genetic FTD
p-015 Marta Pengo Sex influences clinical phenotype in frontotemporal dementia
p-016 Babak Hooshmand Markers of vitamin B12 status in relation to CSF biomarkers and cognitive performance
p-017 Jane Stocks Unique Combinations of Structural MRI-Derived Shape Morphometric Features Improves Discriminability of FTLD Phenotypes
p-018 William J. Scotton Identification of common variants influencing risk of the three-repeat tauopathy Pick’s disease: a genome wide association study.
p-019 Chiara Fenoglio Peripheral inflammatory profile in patients with genetic FTD
p-020 Kamen Tsvetanov Resilience of functional connectomes in presymptomatic frontotemporal dementia
p-021 Valérie Godefroy Apathy dimensions and the connectivity of salience and default-mode networks in behavioural variant frontotemporal dementia
p-022 Lize Jiskoot Longitudinal changes in qualitative aspects of semantic fluency in presymptomatic and prodromal genetic frontotemporal dementia
p-023 Jan Van den Stock Neural compensation in manifest neurodegeneration: evidence from social cognition in frontotemporal dementia
p-024 Jess Jiang Processing of acoustically degraded emotional prosody in primary progressive aphasia and Alzheimer’s disease
p-025 Siddharth Ramanan Identifying white matter signatures of cognitive heterogeneity in primary progressive aphasia: a data-driven transdiagnostic approach
p-026 David Whiteside Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementia
p-027 Costanza Pavone Longitudinal clinical decline and baseline predictors across progressive supranuclear palsy clinical variants
p-028 Edoardo Gioele Spinelli Structural and functional connectome alterations across King’s stages in amyotrophic lateral sclerosis
p-029 Federica Agosta Functional connectivity from disease epicenters in frontotemporal dementia
p-030 Katheryn Cousins Elevated plasma phosphorylated tau 181 in amyotrophic lateral sclerosis relates to lower motor neuron dysfunction
p-031 Enrico Premi Neurotransmitter pattern impairment in prodromal Frontotemporal Dementia: a GENFI study
p-032 Ting Shen Characterizing the progression patterns of cortical atrophy in the ALS-FTD spectrum using SuStaIn model
p-033 Tamara Seredenina Optimization of PET tracers for TDP-43 proteinopathies
p-034 Aitana Sogorb-Esteve Profiling lipid metabolism alterations in genetic FTD within the GENFI cohort.
p-035 Corey McMillan Structure-function decoupling as a marker of neurodegeneration in C9orf72 expansion carriers
p-036 Negin Holland Longitudinal change in synaptic density in primary tauopathies ‘ a [11C]UCB-J PET study.
p-037 Dario Saracino Brain metabolic profile and longitudinal changes in the presymptomatic phase of GRN-associated frontotemporal dementia
p-038 Rubina Malik Cognitive difference in young adult C9orf72 repeat expansion and GRN mutation carriers support neurodevelopmental effects of genetic FTD
p-039 Borna Bonakdarpour Brain hypometabolism and hehavior correlation in primary progressive aphasia
p-040 Vikram Venkatraghavan Data-driven atrophy progression model of sporadic Frontotemporal dementia
p-041 Somayeh Meysami Brain MRI Volumetry Differentiates Behavioral Variant Frontotemporal Dementia from Early Onset Alzheimer’s Disease
p-042 Simon LECERF Diagnostic hesitation between frontotemporal dementia and Alzheimer’s disease. Respective contribution of MRI, FDG-PET and CSF Biomarkers.
p-043 Julio Rojas Clinical value of multiplexed CSF neurodegeneration biomarkers in familial and sporadic frontotemporal dementia
p-044 Peter Ljubenkov Early Results From the ROCKIT-1 Trial: A Phase 2a trial of Fasudil in Patients with Progressive Supranuclear Palsy or Corticobasal Syndrome.
p-045 Lydia Woods MicroRNAs as fluid biomarkers of frontotemporal dementia: a systematic review
p-046 Amira Skeggs Considering the Influence of Culture and Cognitive Reserve on Clinical Presentations of Behavioural-variant Frontotemporal Dementia: A Single-site Study
p-047 Sami Heikkinen Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia
p-048 Golnaz Yadollahikhales 18F-fluorodeoxyglucose-positron emission tomography findings in patients with genetic frontotemporal dementia
p-049 Renard Antoine Cognitive and language disturbances in behavioural variant of Fronto-Temporal Dementia: an update
p-050 Irene Mattioli Amygdala nuclei segmentation in behavioural variant of Frontotemporal Dementia
p-051 Olof Lindberg Reduced BOLD signal in anterior cingulate cortex and anterior insula in behavioral variant frontotemporal dementia when viewing images of hands in painful situations.
p-052 Carolin Heller Growth factors are increased in MAPT-associated FTD
p-053 Emily Todd Progressive white matter changes in MAPT-related frontotemporal dementia: results from the GENFI study
p-054 Andrea Panzavolta Usefulness of socioemotional informant questionnaires for the clinical detection of the behavioural variant of frontotemporal dementia
p-055 Lucia Giannini Clinical value of serum neurofilament light chain in prodromal genetic frontotemporal dementia
p-056 Matthias Schroeter Revisiting dementia praecox - Machine learning reveals links between psychosis and frontotemporal dementia
p-057 Ramiro Ruiz-Garcia Depression in patients with Frontotemporal dementia subtypes
p-058 Sanjana Shellikeri Automated vowel articulation features during natural speech as markers of bulbar motor disease in ALS
p-059 Robert Jr Laforce The PPA Platform: A unique knowledge translation tool on PPA
p-060 Adit Friedberg Emergent visual creativity in frontotemporal dementia is associated with dorsomedial visual cortex enhancement
p-061 Markus Otto Relationship of serum Beta-Synuclein with blood biomarkers and brain atrophy in frontotemporal lobar degeneration and Alzheimer’s disease
p-062 Mark Eldaief FTP tau PET imaging in symptomatic and asymptomatic MAPT mutation carriers
p-063 Rachel Acuna-Narvaez The Neurofilament Surveillance Project (NSP): A biomarker study to sample blood quarterly in familial frontotemporal lobar degeneration
p-064 Lawren VandeVrede Alzheimer’s Disease Biomarkers in 4-Repeat Tauopathy Syndromes: Results from the 4R-Tau Neuroimaging Initiative (4RTNI)
p-065 Soojung Yu Investigating differential effects of oxytocin on improving empathy deficits across structural and functional subtypes of frontotemporal dementia
p-066 Agustina Legaz Social and non-social working memory in neurodegeneration
p-067 Bradley Boeve Memory performance in a symptomatic and prodromal familial frontotemporal dementia: findings from the ALLFTD Consortium
p-068 Toji Miyagawa Characterization of CDR plus NACC FTLD at Phenoconversion from Asymptomatic to Mild Behavioral and/or Cognitive Impairment in familial FTLD: Data from the ALLFTD Consortium
p-069 Hyunwoo Lee FLAIR-MRI and neuropsychiatric changes in predementia frontotemporal dementia mutation carriers approaching clinical conversion
p-070 Michelle Naessens 7T imaging in progressive supranuclear palsy and behavioural variant frontotemporal dementia
p-071 Abbe Ullgren Association of novel CSF biomarker candidates with cortical thickness in genetic frontotemporal dementia
p-072 Sune Skeldal Investigation of the impact of reduced levels of progranulin in mice and patient-derived cells
p-073 Mengjie Huang Changes in amygdalar integrity in frontotemporal dementia subtypes
p-074 Ramon Landin-Romero Trajectories of brain changes predicting distinct pathology subtypes in frontotemporal dementia
p-075 Miguel E. Renteria Genetic overlap between cortical brain morphometry and frontotemporal dementia risk
p-076 Sterre de Boer Diagnostic and prognostic precision medicine for behavioral variant frontotemporal dementia: the DIPPA-FTD study
p-077 Dean Southwood Peripheral monitoring of neurodegeneration in early-onset dementias using cell-free DNA
p-078 Nick Corriveau-Lecavalier Neurite-based white matter alterations in asymptomatic MAPT mutation carriers: A multi-shell diffusion MRI with NODDI study
p-079 Jennie Olofsson CSF protein profiles in relation to disease progression rates in patients with amyotrophic lateral sclerosis
p-080 Sofia Bergström Protein signatures across multiple neurodegenerative diseases
p-081 Sára Mravinacová Deciphering CSF protein signatures in FTD
p-082 Wouter De Coster Somatic variation in the brain of FTLD-TDP patients
p-083 Cristian Leyton When words don’t come easy: Word finding difficulties in Primary Progressive Aphasia
p-084 Gabor Kovacs Neuropathology of Protracted Course-Progressive Supranuclear Palsy (PC-PSP)
p-085 Indira Garcia Cordero Hippocampal vulnerability in Progressive Supranuclear Palsy with Alzheimer’s disease co-pathology
p-086 Rachel Fremont Examining the neural substrates and behavioral correlates of poor driving in Frontotemporal Dementia
p-087 Katherine Stockton Metabolomic effects of sporadic, genetic and pre-symptomatic frontotemporal dementia
p-088 David Irwin Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology
p-089 Neguine Rezaii A syntax-lexicon tradeoff in language production
p-090 Marie-Paule van Engelen Altered fronto-temporo-striatal brain metabolism in behavioral variant frontotemporal dementia and primary psychiatric diseases
p-091 Evan Udine Long-read sequencing of human frontal cortex tissue in C9orf72-related diseases
p-092 Alexandra Touroutoglou Neuroanatomical predictors of progression to dementia in Primary Progressive Aphasia
p-093 Maurice Pasternak A Longitudinal Analysis of Regional Cerebral Perfusion in Genetic Frontotemporal Dementia: Results from GENFI
p-094 Jolina Lombardi Salience network alterations in young adult presymptomatic FTLD mutation carriers
p-095 Jesse Brown Atrophy-driven functional network imbalances in neurodegenerative disease
p-096 Arabella Bouzigues Evidence for early functional connectivity pattern changes in frontotemporal dementia using connectome gradient mapping
p-097 Diego Lorca-Puls Mapping characteristic speech-language features of the nonfluent/agrammatic variant primary progressive aphasia to their neural substrates
p-098 Andrea Gajardo-Vidal Using a tablet-based task to investigate aspects of non-verbal cognition and its neural correlates in primary progressive aphasia
p-099 Jessica Bove Repetitive head impact exposure in patients with frontotemporal dementia spectrum diagnoses
p-100 Maria Luisa Mandelli Network anatomy in the logopenic variant of primary progressive aphasia
p-101 Ashlin R. K. Roy Lower baseline parasympathetic activity in C9orf72 hexanucleotide repeat expansion carriers relates to smaller left frontoinsula gray matter volume and lower empathy
p-102 Brigid Ryan The New Zealand Genetic Frontotemporal Dementia Study (FTDGeNZ): study protocol, and baseline demographic and clinical characteristics
p-103 Kirrie Ballard Longitudinal analysis of grammatical changes across the three variants of Primary Progressive Aphasia
p-104 Fatemeh Noohibezanjani Atypical facial behaviors in C9orf72 hexanucleotide repeat expansion carriers have diffuse neural representations in primary motor cortex
p-105 Patrick Oeckl Longitudinal profile of blood biomarkers in primary progressive aphasias and relation to brain atrophy and cognitive impairment
p-106 Peter Pressman Conversational turn-taking in frontotemporal dementia and related disorders
p-107 Kathryn Knowles Chemokine CSF concentrations are abnormal in genetic FTD within the GENFI cohort
p-108 Sol Fittipaldi Multicentric evidence on multimodal predictors of social cognition in the behavioral variant frontotemporal dementia and Alzheimer’s Disease
p-109 Liwen Zhang Network connectivity alterations in presymptomatic and symptomatic MAPT mutation carriers
p-110 Rodrigo Santibanez Tau PET imaging with 18F-PI-2620 in patients with corticobasal syndrome compared to patients with Alzheimers disease and healthy controls
p-111 Laynie Dratch Genetic evaluation of FMR1 in a person presenting with symptoms of frontotemporal degeneration.
p-112 Olga Uspenskaya Phase 1/2 Study Update of an AAV9-Based Gene Therapy for Fronto-Temporal Dementia with Pathogenic GRN Mutations (PROCLAIM Trial)
p-113 Myrthe G. Rijpma Distinct emotion regulation profiles in patients with FTLD syndromes and psychiatric disorders: initial ALLFTD neuropsychiatric data
p-114 Masood Manoochehri TMEM106B haplotype alters disease penetrance in FTLD-GRN mutation carriers
p-115 Simrika Thapa Investigation of neuroinflammatory markers in Frontotemporal Lobar Degeneration (FTLD)
p-116 Chloe Anastassiadis Imaging and CSF markers contributing to clinical heterogeneity in frontotemporal dementias
p-117 Alexandria O’Neal Vagus nerve stimulation effects on functional connectivity in mild cognitive impairment: The role of cerebral metabolites

Lille - Friday Nov. 04, 2022 

p-239 Miguel Minaya Conserved gene signatures shared among MAPT mutations reveals defects in calcium signalingp-240 Linnea Hjelm Generation of affibody molecules that sequester targets involved in neurodegenerative disorders
p-241 Vivek Swarup Single-cell epigenomics identifies shared changes in Alzheimer’s and Pick’s disease
p-242 Suborno Jati Depletion of ChromograninA (CgA) reduces Tau mediated neurodegeneration in vivo
p-243 Conceição Bettencourt Epigenome-wide association studies identify differentially methylated loci across frontotemporal lobar degeneration subgroups
p-244 Morvane Colin Heterogeneity in tau spreading among tauopathies; the place of extracellular vesicles
p-245 Ivana Kancheva Distinct patterns of cerebrovascular reactivity alterations in pre-symptomatic and symptomatic familial frontotemporal dementia
p-246 Emma Gerrits Transcriptomic characterization of GRN-associated frontotemporal dementia brain tissues
p-247 Anarmaa Mendsaikhan Generation of anti-Progranulin camelid nanobodies
p-248 Sebastian Boland Deficiency of GRN, a frontotemporal dementia gene, results in gangliosidosis
p-249 Anna Volkmer Results of the Better Conversations with Primary Progressive Aphasia (BCPPA) pilot-feasibility trial: Communication Partner Training to keep families together
p-250 Babak Hooshmand Markers of vitamin B12 status in relation to CSF biomarkers and cognitive performance
p-251 Ashley Viera Ortiz Impaired ribosome-associated quality control of C9orf72-associated arginine-rich dipeptide-repeat proteins
p-252 William Seeley Reproducibility of FTLD-TDP subtypes among experienced diagnosticians
p-253 Sanaz Arezoumandan Hippocampal distribution of tau pathology in FTLD tauopathies
p-254 Laura Marriott Identification of primary tauopathy cases in the New Zealand Neurological Foundation Human Brain Bank
p-255 Jolien Schaeverbeke Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer’s disease neuropathological changes
p-256 Constance Delaby NfL as a blood biomarker for FTD and others neurodegenerative diseases in primary psychiatric context.
p-257 Benjamin Creekmore Small molecule activation of valosin-containing protein (VCP)
p-258 Yuliya Shpilyukova Structural and functional cerebellar changes in non-C9orf72 FTD patients
p-259 Maria Italia Anti-GluA3 antibodies in Frontotemporal Dementia: an in vivo approach
p-260 Daniel Ohm Tauopathies and TDP-43 proteinopathies cause distinct patterns of projection neuron degeneration in behavioral variant frontotemporal dementia
p-261 Lauren M. Forgrave In vivo proteolytic fragments of TDP-43 as diagnostic biomarkers of frontotemporal dementia
p-262 Akhil Bhalla Identification of novel FTD-GRN patient biomarkers via multi-omics approaches
p-263 Lisa Oyston TDP-43 subcellular mislocalisation is correlated with loss of optineurin binding for frontotemporal dementia and amyotrophic lateral sclerosis associated TBK1 missense variants
p-264 Dorit Hoffmann Fibroblasts from C9orf72 hexanucleotide repeat expansion intermediate and full-length carriers show impaired energy metabolism
p-265 Maria Serpente Neural Derived Extracellular Vesicles and their miRNAs cargo in Frontotemporal Dementia and Bipolar Disorder: an exploratory study
p-266 Ariana Gatt HnRNPK mislocalisation leads to cryptic exon inclusion in FTLD post-mortem brains.
p-267 Andrew Arrant Regulation of extracellular progranulin in the brain
p-268 Sophie Halliez Revisiting tau involvement in complex neural network remodelling through the analysis of extra-cellular neuronal activity exhibited by organotypic brain slice co-cultures
p-269 David Dai Single nucleus transcriptome analysis of human reactive astrocytes
p-270 Antonia Zouridakis Anatomic selectivity of neuronal and glial tau in Primary Progressive Aphasia with 4R FTLD-tauopathies
p-271 Victoria Light Serum neurofilament light as a diagnostic biomarker to differentiate frontotemporal dementia from primary psychiatric disorders
p-272 Grace Minogue Burden of pathology in hippocampal subregions can distinguish amnestic dementia with comorbid Alzheimer’s and TDP-43 pathology from pure Alzheimer’s and FTLD-TDP
p-273 Ludmilla Araujo Generation and characterization of mono-specific antibodies to analyze the abundance and function of human granulins
p-274 Felipe Pereira L5ET neurons show distinct yet overlapping gene expression profiles in ACC, FI, PreCG and V1
p-275 Luc BUEE Anti-tau nanobodies for targeting intracellular aggregates in tauopathies
p-276 J. Casey The role of Progranulin in PINK1/Parkin mitophagy
p-277 Paula Polanco Miquel Progranulin mutations in microglia and its impact in neurodegeneration
p-278 Sharifah anoar Understanding C9orf72 Hexanucleotide Repeat Linked to Mitochondrial Dysfunction
p-279 Kohji Mori siRNA-knockdown screening for potential RAN translation modulators in cellular models of C9orf72 FTLD/ALS
p-280 Jolien Perneel Animal models of TMEM106B confirm functional effect of the p.T185S variant and show that increased TMEM106B protein levels lead to severe lysosomal dysfunction in vivo.
p-281 Cristina T. Vicente Methylome analysis of FTLD patients with TDP-43 pathology (FTLD-TDP) implicates the hexosamine biosynthetic pathway in disease
p-282 Merel Mol Neuropathological burden in presymptomatic and early-stage frontotemporal lobar degeneration with MAPT pathogenic variants
p-283 Luigi Fiondella The presence of extrapyramidal symptoms is linked to a higher TDP-43 burden in the substantia nigra of FTLD-TDP brain donors.
p-284 Carol Dobson-Stone FTD-ALS mutation CYLD p.M719V increases necroptosis-like cell death
p-285 Shiho Gotoh Functional analysis of a potential RAN translation regulator in C9orf72 FTLD/ALS
p-286 Moira Ek Design of an anti-sortilin affibody-peptide fusion construct for inhibition of sortilin-mediated progranulin degradation
p-287 Vishaal Sumra Assessing neuroinflammatory differences in FTLD-Tau vs FTLD-TDP using free water diffusion
p-288 Matthew Simon Rescue of FTD-GRN associated phenotypes in a mouse model of PGRN deficiency with the brain penetrant progranulin biologic DNL593
p-289 Teresa Niccoli A monocarboxylate transporter modifies C9orf72 repeat expansion toxicity
p-290 Oriol Dols-Icardo Transcriptome wide correlations with FTLD-TDP, FTLD-C9 and FTLD-tau neuropathological hallmarks in the frontal cortex of FTLD patients
p-291 Christopher Olm Event-based modeling of in vivo MRI measures is associated with pathologic burden in frontotemporal lobar degeneration due to tau
p-292 Paola Merino The granulin linker region is necessary for proper folding, trafficking, and rescue of lysosome dysfunction
p-293 Evan Udine RNA sequencing of the human cerebellum reveals transcriptomic and cellular alterations in C9orf72 expansion carriers
p-294 Allegra Kawles Trajectories of neurocognitive decline in aphasic versus behavioral dementia syndromes due to Pick disease
p-295 Miranda Lastra Osua Role of TMEM106B on neuronal susceptibility to degeneration in FTLD
p-296 Alireza Faridar Restoring Dysfunctional Regulatory T cells Through Ex Vivo Expansion in Frontotemporal Dementia
p-297 Linn Öijerstedt Alterations in global EEG power and synchronization in C9orf72 and GRN mutation carriers.
p-298 Udit Sheth Examining the role of PABPC4 as a TDP-43 modifier in FTLD-TDP
p-299 Divya Brundavanam Cortical atrophy and altered functional connectivity in the salience network in bvFTD
p-300 Jeffrey Phillips White matter tau pathology mediates inter-regional tau associations in clinically heterogeneous Alzheimer’s disease
p-301 Adam Martersteck Epicenters of cortical atrophy in primary progressive aphasia differ by underlying neuropathology
p-302 Marta Scarioni Motor neuron symptoms are linked to pathology burden in the medulla oblongata of FTLD-TDP brain donors
p-303 Laura Cracco Post-translational modifications of TDP-43 in hereditary frontotemporal dementia
p-304 Ashlin R. K. Roy Behavioral subphenotypes and their anatomic correlates in neurodegenerative disease
p-305 Terunori Sano An autopsy case of TDP43 proteinopathy presenting progressive supranuclear palsy
p-306 Rachel Keszycki Activation of microglia in amygdala is concordant with behavioral/comportmental dementia symptoms due to underlying Pick disease
p-307 Jane Stocks Spatial and temporal relationships between atrophy and hypometabolism in behavioral-variant frontotemporal dementia
p-308 Yu Chen Cerebellar atrophy in pathological subtypes of frontotemporal lobar degeneration
p-309 Thibaud Lebouvier Clinicopathological correlations in frontotemporal lobar degeneration: results from a French cohort with deep clinical and behavioural phenotyping
p-310 Abraham Scaria AAVrh10 based progranulin delivery to the central nervous system for the treatment of  frontotemporal dementia caused by GRN mutations
p-311 Sarat Vatsavayai Characterizing STMN2 protein expression and cryptic splicing in neurons vulnerable to FTLD-TDP and ALS
p-312 Vincent LE DU Multi-atlas Multilayer Brain Networks, a multimodal approach to brain connectivity in frontotemporal dementia and Alzheimer’s disease.
p-313 Anke Dijkstra TDP-43 aggregation in the retina of patients with FTLD-TDP
p-314 Lena Szabó Exploring the presence of frontotemporal lobar degeneration associated proteinopathies in the skin: the skin as a possible biomarker for FTD?
p-315 NICHOLAS BOYLE Abnormalities in glycosphingolipid degradation caused by progranulin deficiency
p-316 Ashley Heywood Regression analysis identifies association between postmortem amyloid-beta burden and antemortem fractional anisotropy within forceps minor
p-317 Yeliz Aydemir Progranulin upregulation by antisense oligonucleotides targeting regRNAs for treatment of FTD-GRN
p-318 David Irwin Machine learning quantification of tau-positive glia and neuronal inclusions in PSP
p-319 Stephanie Gaus Tuberous Sclerosis Complex (TSC) is associated with a novel human tauopathy
p-320 Shreya Kashyap Neuronal transduction of AAV-Progranulin rescues pro-inflammatory microglial morphology in a mouse model of progranulin deficiency
p-321 Anders Toft Endo-lysosomal proteins and ubiquitin in CSF from patients with frontotemporal dementia caused by CHMP2B mutation (FTD-3)
p-370 Carlos Miranda Intrathalamic delivery of AVB-101 rescues pathology in progranulin deficient mice and achieves widespread cortical expression in two large animal models.
p-371 Elise Marsan Conserved astroglial toxicity promotes synaptic degeneration in frontotemporal dementia with GRN mutations
p-372 Ambika Tewari A baculovirus-produced gene therapy vector PR006A demonstrates efficacy and tolerability in mouse and NHP studies
p-373 Chris Hardy Symptom-staging for primary progressive aphasia syndromes
p-374 Li Niu Testing RNA Aptamers in an animal model with TDP-43 pathology
p-375 Pallabi Bhattacharyya Ca2+/Calcineurin mediated release of astrocytic miR-23a regulates neuron-glia cross-talk and is increased in the exosomes derived from Parkinson's patient plasma
p-376 Luke Harper Prenatal neurodevelopmental brain reserve influences disease expression in behavioral variant Frontotemporal Dementia (bvFTD)
p-377 Jean-François Blain Characterization of ARK-1252, a novel small molecule enhancer of progranulin for the treatment of frontotemporal dementia
p-378 Francesco Di Lorenzo Effects of Palmitoylethanolamide Combined with Luteoline on High Frequency Oscillations and GABAergic Transmission in Patients with Frontotemporal Dementia
p-379 Francesco Di Lorenzo Transcranial magnetic stimulation distinguishes patients with behavioral variant of frontotemporal dementia from Primary Progressive Aphasia patients
p-380 Simrika Thapa Distinct neuroinflammatory mechanisms in Frontotemporal Lobar Degeneration and Alzheimer's Disease
p-381 Martina Assogna Choroid plexus volume as a potential novel biomarker in frontotemporal lobar degeneration
p-382 Lisanne Jenkins Apathy and disinhibition associated with salience and cognitive control network morphometric similarity across dementias
p-383 Leslie Sanderson Somatic N-terminal TARDBP variants identified in the brain of FTD-TDP-C patients disrupt physiological function in zebrafish

Lille - Saturday Nov. 05, 2022

p-118 mohamad el haj Pupil dilates with increased cognitive processing in a case with behavioral variant FrontoTemporal Dementia
p-119 Claire Boutoleau-Bretonniere Aesthetic judgements in patients with behavioral variant of Frontotemporal Dementia in front of abstract or figurative paintings.
p-120 Argye Hillis Intra-individual asymmetries in distinct regions of interest are associated with each variant of primary progressive aphasia
p-121 Kiran Samra Developing the neuropsychiatric and motor components of clinical rating scales in frontotemporal dementia
p-122 Catherine MERCK Why the semantic dementia syndrome should not become obsolete
p-123 Vanina Ramognino Catatonia, a differential diagnosis of fast FTLD progression
p-124 Helmi Soppela Traumatic brain injury associates with an earlier onset in sporadic frontotemporal dementia
p-125 Jeanne Gallée «Please don’t assess him to destruction»: introducing the R.A.I.S.E. Assessment framework to guide evaluation of people with PPA
p-126 Giorgio Giulio Fumagalli Late onset frontal syndrome: differentiation between Frontotemporal dementia and Primary psychiatric disorder using visual rating scales of atrophy
p-127 Raphael Le Bouc Effort avoidance revealed by behavioral tests as a core mechanism of apathy in frontotemporal dementia
p-128 mazoué aurélien Does a rabbit have feathers or fur? Development of a 42-item semantic memory test (SMT-42)
p-129 Rhian Convery Ignite - a novel computerized cognitive assessment battery for frontotemporal dementia
p-130 Beatrice Taylor How do the activities of daily living change longitudinally in people living with frontotemporal dementia and other rarer dementias? A systematic review.
p-131 Olivia Fegter Suitability of goal attainment scaling in older adult populations with neurodegenerative disease experiencing dementia or cognitive impairment: a systematic review
p-132 Maxime Bertoux NORMS - A neuropsychological assessment of social norms knowledge in FTLD: a preliminary study
p-133 A. Campbell Sullivan Diagnostic delays amongst Hispanics/Latinos with ALS-FTD: Initial cognitive and behavioral findings
p-134 Stephanie Wong Altered reward processing underpins emotional apathy in dementia
p-135 Duncan Street Non-motor markers improve survival prediction in Progressive Supranuclear Palsy
p-136 Zachary Miller Higher prevalence of STEM occupations in frontotemporal dementia compared to Alzheimer’s disease and the US general population.
p-137 Valérie Godefroy Distinct profiles of apathy corresponding to distinct anatomical subtypes of behavioural variant frontotemporal dementia
p-138 Lize Jiskoot The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: a GENFI study
p-139 Daniele Romano Do patients with bvFTD suffer from ‘genuine’ memory deficits? A meta-analytic approach
p-140 Jochum J. van ‘t Hooft Musicality in frontotemporal dementia: results from the MELODIA project
p-141 Badra Outamazirt Validation of the amnesic presentation of behavioral variant FTD
p-142 Patrick Callahan Differentiation and Symptom Progression of bvFTD, svPPA, and nfvPPA Subtypes Using UDS-FTLD Module Behavior Measures
p-143 David Foxe Utility of the Addenbrooke’s Cognitive Examination-III online calculator to differentiate the primary progressive aphasia variants
p-144 Maria Lapid Criminal behaviors in Frontotemporal Dementia: A case report
p-145 Richard Tsai Safety, pharmacokinetics, and pharmacodynamics of a brain penetrant PGRN (DNL593) in healthy volunteers and participants with frontotemporal dementia caused by GRN mutations: Ph1/2 Study Design
p-146 Sophie Goldsmith Using the Sea Hero Quest app to measure spatial navigation and memory impairments in ‘at-risk’ genetic frontotemporal dementia participants from the UK GENFI cohort
p-147 Yong Bum Kim Frontal versus temporal type memory deficit in amnestic mild cognitive impairment; predictive value in the diagnosis of Alzheimer disease using amyloid PET
p-148 Jessica L. Hazelton Interoception but not cognition predicts emotion recognition in behavioural-variant frontotemporal dementia: comparisons with Alzheimer’s Disease and Parkinson’s Disease.
p-149 Lara Raffaella Migliaccio Behavioural disinhibition in frontotemporal dementia investigated within an ecological framework
p-150 Anna Volkmer ‘Going into a chocolate shop, blindfolded.’: Addressing the speech and language therapy needs of people with Primary Progressive Aphasia
p-151 Lina Riedl Comparison of quality-of-life in late-stage dementia in Alzheimer’s disease and Frontotemporal Dementia
p-152 Fiona Kumfor A prospective study of criminal risk behaviours in frontotemporal dementia
p-153 Christopher Morrow Early Psychiatric Symptoms and Illness Progression in Behavioral Variant Frontotemporal Dementia
p-154 Muireann Irish Anhedonia as an early clinical feature of frontotemporal dementia
p-155 Grace Wei The impact of the COVID-19 pandemic on neuropsychiatric symptoms and carer mental health
p-156 Ashleigh O’Mara Baker Early cognitive changes and the status of episodic memory in presymptomatic bvFTD-MAPT: A case-control study
p-157 J Sun Neural functional changes in premanifest C9orf72-repeat expansion carriers
p-158 Victor Altmayer Cognitive components of creativity and structural brain correlates in frontotemporal dementia
p-159 Bénédicte Batrancourt The ECOCAPTURE research program and the generation of behavioral metrics to assess behavior disorders in bvFTD.
p-160 William LUCAS Predictors of survival in the early phase of Semantic Dementia
p-161 Petronilla Battista Characterizing the clinical and neuroimaging profile of progressive dynamic aphasia: a case series
p-162 Katie Rodriguez Apathy and impulsivity overlap in Parkinson’s disease: a case for transdiagnostic approaches in FTD
p-163 Rubina Malik A neurocognitive model for apathy in neurodegenerative dementias: preliminary findings in FTD, LBD, and AD
p-164 Michael Keem Cerebrospinal fluid neurofilament light chain differentiates behavioural variant frontotemporal dementia from ‘phenocopy’ non-progressors
p-165 Monica Lavoie Progression of BPSD is different in early vs late onset svPPA: A retrospective study
p-166 Dhamidhu Eratne The MiND Study bringing NfL and other markers to distinguish bvFTD from phenocopies, and clinical utility in diverse neurodegenerative and psychiatric disorders
p-167 Ramiro Ruiz Progression of Bipolar Disease to Frontal Dementia: A Systematic Review and Provisional Research Criteria
p-168 Peter Ljubenkov Description of the Veri-T: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of Verdiperstat in Patients with svPPA Due to FTLD-TDP
p-169 Elizabeth Poulin Longitudinal portrait of cognitive abilities in the three main PPA variants
p-170 Rik Vandenberghe Consistency of drug treatment decisions for behavioral disturbances in frontotemporal dementia within the Frontotemporal Dementia European Rare Disease Network (ERN-RND)
p-171 Corey McMillan Disparities in frequency of neuropsychiatric symptoms in black and white individuals
p-172 Mika Konishi A probable case of phenocopy syndrome of behavioral variant frontotemporal dementia
p-173 Jan Van den Stock Social cognition workgroup of neuropsychiatric international consortium on frontotemporal dementia (scNIC-FTD): open call for clinical optimization of social cognition assessment
p-174 Jess Jiang The speech-to-song illusion in frontotemporal dementia and Alzheimer’s disease
p-175 Meghana Rao Effects of the COVID-19 pandemic on caregiver burden in frontotemporal degeneration: Findings from the ALLFTD consortium
p-176 Jingxuan Wang Nonlinear Z-score Modeling Minimizes Ceiling and Floor Effects of the Uniform Data Set Neuropsychological Measures for Frontotemporal Lobar Degeneration (FTLD)-Spectrum Disorders
p-177 Shalom Henderson Verbal fluency as a ‘cognitive ESR’: examination of fluency deficits in six neurodegenerative disorders
p-178 Sara Rubio Guerra Klinefelter syndrome: a novel cause of the behavioral variant of frontotemporal dementia phenocopy syndrome
p-179 Sylvia Josephy-Hernandez Automated analysis of functional written communication and a comparison to spoken communication in the three variants of primary progressive aphasia
p-180 Tony Phan Measuring the extent and severity of antisocial behaviors in behavioral-variant frontotemporal dementia using a novel informant-based questionnaire
p-181 Hyunwoo Lee Progression of cognitive changes in predementia GRN and C9orf72 mutation carriers
p-182 Jerica Reeder Increased social vulnerability in behavioral-variant frontotemporal dementia
p-183 Claudia Meli Mini-Frontal Behavioral Inventory supports early identification of different behavioral phenotypes in the behavioral variant of frontotemporal dementia
p-184 Liset de Boer The Social Norms Questionnaire-Dutch version (SNQ-NL) as neuropsychological marker for Frontotemporal Dementia.
p-185 Courtney Lewis Mealtime assessment of aberrant eating behaviours and their impact on swallow safety
p-186 Paul Tristin Best Longitudinal Changes in Brain Structure Reflect Differential Patterns of Behavioural and Neuropsychiatric Symptom Change in Genetic Frontotemporal Dementia
p-187 Emma Johnson Sensitivity to social reputation motivates prosocial engagement in behavioural-variant frontotemporal dementia
p-188 Jay Fieldhouse Impaired emotion recognition and facial expression processing: behavioral variant frontotemporal dementia versus primary psychiatric disorders and controls
p-189 Malik Nassan Genetic link between asymmetry and handedness genes and agrammatic primary progressive aphasia: a mendelian randomization approach
p-190 Manisha Narasimhan The clinical spectrum of movement disorder in initial presentation of suspected Frontotemporal Lobar Degeneration (FTLD)-Tauopathy
p-191 Rachel Fremont A cross-sectional exploration of obsessive and compulsive symptoms in FTLD-spectrum disorders
p-192 Cristian Leyton Non-fluent variant of primary progressive aphasia ‘ is there a right syndrome?
p-193 Belen Pascual Neuroinflammation in frontotemporal lobar degeneration: A 11C-PBR28 positron emission tomography study
p-194 Noora-Maria Suhonen The modified Frontal Behavioral Inventory in the follow-up of working-aged memory clinic patients
p-195 Lorna Garcia-Penton Deconstructing the transdiagnostic nature of language symptoms on frontotemporal lobar degeneration syndromes
p-196 Shunsuke Sato Characteristics of psychosis in sporadic frontotemporal dementia
p-197 Leonardo Cruz de Souza Social cognition across bipolar disorder and behavioral variant frontotemporal dementia: an exploratory study.
p-198 Stephanie Grasso Examining the effects of restitutive speech-language interventions in culturally and linguistically diverse individuals with primary progressive aphasia
p-199 Maxime Montembeault The characteristic social functioning profiles in each primary progressive aphasia variant
p-200 Pauline Saliou Social norms recognition judgment in frontotemporal dementia and semantic variant of primary progressive aphasia
p-201 Dirk van Paassen Clinically preferred pharmacological treatment for behavioral symptoms in bvFTD
p-202 John Kornak Clinical relevance of demographically adjusted nonlinear Z-scores for cognitive testing of patients with FTLD-spectrum disorders
p-203 Caroline V Greaves Autistic traits and schizotypy in presymptomatic familial frontotemporal dementia
p-204 Marine Le Petit Behavioral and brain changes related to mindreading in presymptomatic C9ORF72 carriers
p-205 Andrea Gajardo-Vidal Left prefrontal regions mediate the influence of executive functioning on sentence processing in primary progressive aphasia
p-206 Idil Sezer Ecocapture@home research program: assessing behavioral markers of apathy in bvFTD patient-caregiver dyads under everyday life conditions.
p-207 Rebecca Khayum Stakeholder perspectives: National Aphasia Association primary progressive aphasia advisory board and survey results
p-208 Maud Tastevin Evolution of behavioral and psychological symptoms of dementia in the non-fluent variant of primary progressive aphasia
p-209 Golnaz Yadollahikhales Perceptual and semantic deficits in face recognition in semantic dementia patients
p-210 Maria Beers Psychosocial Effects on FTD Families
p-211 Renard Antoine Language and Communication Acquired Disturbances Inventory (LaCADI)
p-212 Leah Forsberg Analyses of Quality of Life in Frontotemporal Lobar Degeneration: Findings from the ALLFTD Consortium
p-213 Katherine Brandt Nothing about us without us: giving voice to persons with a diagnosis, family members and care partners through research participation
p-214 Bonnie Wong Advance care planning and medical decision-making in the era of COVID-19: use of video tools for guiding dementia caregivers
p-215 Anna-Leena Heikkinen Utility of the INECO Frontal Screening (IFS) and Frontal Assessment Battery (FAB) in detecting executive dysfunction in early-onset cognitive impairment and dementia
p-216 Tania Gendron Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders
p-217 Peter Pressman Symptomatic progression of FTD with the TARDBP I383V variant
p-218 Hilary Heuer Phenoconversion observed over longitudinal follow-up in mutation carriers of familial Frontotemporal Lobar Degeneration in the ALLFTD Consortium,
p-219 Julie Huang Results from the phase 2 study of latozinemab (AL001) in frontotemporal dementia patients carrying a granulin mutation
p-220 Neguine Rezaii A syntax-lexicon trade-off in language production
p-221 17173410696 Flaherty Myotonic Dystrophy-1 as a model of frontotemporal degeneration in non-coding region microsatellite diseases with motor involvement
p-222 Stella McCaughey Design of INFRONT-3: A phase 3 randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of latozinemab in FTD-GRN
p-223 Durjoy Lahiri 4 mA tDCS with executive training collaterally improves naming scores in logopenic variant primary progressive aphasia (lvPPA): A case study
p-224 Lawrence Carter Twelve-Month Results from the INFRONT-2 Phase 2 Open-Label Study of Latozinemab (AL001) in Frontotemporal Dementia Participants with C9orf72 Repeat Expansions
p-225 Adam Staffaroni Reliability and Validity of the ALLFTD Mobile App Cognitive Tests
p-226 Ramon Landin-Romero Brain changes underlying progression of speech motor programming impairment
p-227 Monica Consonni Loneliness is associated with behavioral dysfunctions and thinning of the frontoparietal cortex in amyotrophic lateral sclerosis.
p-228 Maryna Polyakova Discriminating primary progressive aphasia subtypes with patholinguistic tests and structural MRI
p-229 Brian Tracey Novel approaches to characterizing acoustic and linguistic features of FTD speech
p-230 Saira Mirza Rare variant burden contributes to frontal and temporal lobe volumes in genetic frontotemporal dementia: Results from GENFI
p-231 Myrthe G. Rijpma Emotion regulation in frontotemporal dementia relies on semantic knowledge and control systems in the brain
p-232 Emma Rhodes Interpersonal reactivity index, autonomic, and metabolic function in pre-symptomatic frontotemporal degeneration
p-233 Miguel Angel Santos-Santos Deconstructing agrammatism in primary progressive aphasia
p-234 Alexandre Morin Distinguishing neurological diseases from primary psychiatric disorders: new insights from a cohort of neurological diseases presenting as a psychiatric disorder.
p-235 Colin Stein Financial Behaviors and Experiences of Financial Loss in those with Alzheimer’s disease and Frontotemporal Dementia: Preliminary findings from a survey.
p-236 Jaden Mann Bryant Prevalence of psychiatric disorders in genetic FTLD kindreds
p-237 Julie Fields Cognitive trajectories of familial frontotemporal lobar degeneration mutation carriers: data from the ALLFTD Consortium
p-238 Darby Morhardt PPA Tele-Savvy: Piloting an Online Intervention with Care Partners of Persons Living with Primary Progressive Aphasia